APPLIED ASPECTS OF SLCO1B1 PHARMACOGENETIC TESTING FOR PREDICTING OF STATIN-INDUCED MYOPATHY AND PERSONALIZATION OF STATINS THERAPY

The clinical significance of the SLCO1B1 gene polymorphism (encoding an organic anion transport polipeptide) in the development of statin induced myopathy is considered. Possible tactics of statin dose determination on the basis of pharmacogenetic testing is discussed. Indications for the use of thi...

Descrizione completa

Dettagli Bibliografici
Autori principali: D. A. Sychev, G. N. Shuev, A. B. Prokofiev
Natura: Articolo
Lingua:English
Pubblicazione: Столичная издательская компания 2015-09-01
Serie:Рациональная фармакотерапия в кардиологии
Soggetti:
Accesso online:https://www.rpcardio.online/jour/article/view/299