The Role of Quality Control in Targeted Next-generation Sequencing Library Preparation

The Role of Quality Control in Targeted Next-generation Sequencing Library Preparation

Next-generation sequencing (NGS) is getting routinely used in the diagnosis of hereditary diseases, such as human cardiomyopathies. Hence, it is of utter importance to secure high quality sequencing data, enabling the identification of disease-relevant mutations or the conclusion of negative test re...

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Bibliographic Details
Main Authors: Rouven Nietsch, Jan Haas, Alan Lai, Daniel Oehler, Stefan Mester, Karen S. Frese, Farbod Sedaghat-Hamedani, Elham Kayvanpour, Andreas Keller, Benjamin Meder
Format: Article
Language:English
Published: Oxford University Press 2016-08-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Next-generation sequencing
Quality control
Library preparation
Target enrichment
Sequence variants
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022916301073

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http://www.sciencedirect.com/science/article/pii/S1672022916301073

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