Syrosingopine and UK5099 synergistically suppress non-small cell lung cancer by activating the integrated stress response

Abstract Non-small cell lung cancer (NSCLC) presents a global health challenge due to its low five-year survival rates, underscoring the need for novel therapeutic strategies. Our research explored the synergistic mechanisms of syrosingopine and UK-5099 in treating NSCLC. In vitro experiments showed...

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Bibliographic Details
Main Authors: Yiman Li, Yan Song, Zhijing Shi, Huijie Hou, Yang Yu, Fei Pan, Jinlu Ji, Zhe Chen
Format: Article
Language:English
Published: Nature Publishing Group 2024-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06821-4