Immunoproteasome inhibition attenuates experimental psoriasis
IntroductionPsoriasis is an autoimmune skin disease associated with multiple comorbidities. The immunoproteasome is a special form of the proteasome expressed in cells of hematopoietic origin.MethodsThe therapeutic use of ONX 0914, a selective inhibitor of the immunoproteasome, was investigated in C...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.1075615/full |