Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors’ susceptibility

Abstract Background The methylenetetrahydrofolate reductase (MTHFR) rs1801131 A/C variant results in a decrease in MTHFR enzymatic activity, which may play an important role in folate metabolism and is also an important source of DNA methylation and DNA synthesis. Several case-control studies have b...

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Bibliographic Details
Main Authors: Shuaili Xu, Li Zuo
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Hereditas
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41065-020-00129-x