Effect of Physical Activity on Plasma PCSK9 in Subjects With High Risk for Type 2 Diabetes

BackgroundProprotein convertase subtilisin/kexin type 9 (PCSK9) is a liver serine protease regulating LDL cholesterol metabolism. PCSK9 binds to LDL receptors and guides them to lysosomes for degradation, thus increasing the amount of circulating LDL cholesterol. The aim of the study was to investig...

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Bibliographic Details
Main Authors: Kari Antero Mäkelä, Juhani Leppäluoto, Jari Jokelainen, Timo Jämsä, Sirkka Keinänen-Kiukaanniemi, Karl-Heinz Herzig
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00456/full