A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung

A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung

Abstract We present an in-depth single-cell atlas of in vitro multiculture systems on human primary airway epithelium derived from normal and diseased lungs of 27 individual donors. Our large-scale single-cell profiling identified new cell states and differentiation trajectories of rare airway epith...

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Bibliographic Details
Main Authors: Woochan Lee, Seyoon Lee, Jung-Ki Yoon, Dakyung Lee, Yuri Kim, Yeon Bi Han, Rokhyun Kim, Sungji Moon, Young Jun Park, Kyunghyuk Park, Bukyoung Cha, Jaeyong Choi, Juhyun Kim, Na-young Ha, Kwhanmien Kim, Sukki Cho, Nam-Hyuk Cho, Tushar J. Desai, Jin-Haeng Chung, Joo-Hyeon Lee, Jong-Il Kim
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01076-z

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https://doi.org/10.1038/s12276-023-01076-z

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