A single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung
Abstract We present an in-depth single-cell atlas of in vitro multiculture systems on human primary airway epithelium derived from normal and diseased lungs of 27 individual donors. Our large-scale single-cell profiling identified new cell states and differentiation trajectories of rare airway epith...
Main Authors: | Woochan Lee, Seyoon Lee, Jung-Ki Yoon, Dakyung Lee, Yuri Kim, Yeon Bi Han, Rokhyun Kim, Sungji Moon, Young Jun Park, Kyunghyuk Park, Bukyoung Cha, Jaeyong Choi, Juhyun Kim, Na-young Ha, Kwhanmien Kim, Sukki Cho, Nam-Hyuk Cho, Tushar J. Desai, Jin-Haeng Chung, Joo-Hyeon Lee, Jong-Il Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
|
Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-023-01076-z |
Similar Items
-
Multidimensional fragmentomic profiling of cell-free DNA released from patient-derived organoids
by: Jaeryuk Kim, et al.
Published: (2023-10-01) -
Expression-based species deconvolution and realignment removes misalignment error in multispecies single-cell data
by: Jaeyong Choi, et al.
Published: (2022-05-01) -
Impact of idiopathic pulmonary fibrosis on recurrence after surgical treatment for stage I-III non-small cell lung cancer.
by: Myung Jin Song, et al.
Published: (2020-01-01) -
Poor Prognosis of Grade 2 Spread Through Air Spaces in Neuroendocrine Tumors
by: Mincheol Chae, et al.
Published: (2022-04-01) -
Placental expression quantitative trait loci in an East Asian population
by: Jaeyong Choi, et al.
Published: (2024-04-01)