GDNF-RET signaling and EGR1 form a positive feedback loop that promotes tamoxifen resistance via cyclin D1

Abstract Background Rearranged during transfection (RET) tyrosine kinase signaling has been previously implicated in endocrine resistant breast cancer, however the mechanism by which this signaling cascade promotes resistance is currently not well described. We recently reported that glial cell-deri...

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Bibliographic Details
Main Authors: Brooke A. Marks, Ilissa M. Pipia, Chinatsu Mukai, Sachi Horibata, Edward J. Rice, Charles G. Danko, Scott A. Coonrod
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-10559-1