Alterations of Striatal Subregions in a Prion Protein Gene V180I Mutation Carrier Presented as Frontotemporal Dementia With Parkinsonism

Alterations of Striatal Subregions in a Prion Protein Gene V180I Mutation Carrier Presented as Frontotemporal Dementia With Parkinsonism

ObjectiveTo explore the roles of striatal subdivisions in the pathogenesis of frontotemporal dementia with parkinsonism (FTDP) in a patient resulting from prion protein gene (PRNP) mutation.MethodsThis patient received clinical interviews and underwent neuropsychological assessments, genetic testing...

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Bibliographic Details
Main Authors: Zhongyun Chen, Jinghong Ma, Li Liu, Shuying Liu, Jing Zhang, Min Chu, Zhen Wang, Piu Chan, Liyong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
frontotemporal dementia with parkinsonism
prion protein gene
striatum
dopamine
positron emission tomography
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.830602/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.830602/full

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