Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers

Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers

Altered myofibrillar structure is a consequence of dystrophic pathology that impairs skeletal muscle contractile function and increases susceptibility to contraction injury. In murine Duchenne muscular dystrophy (mdx), myofibrillar alterations are abundant in advanced pathology (>4 months), a...

Full description

Bibliographic Details
Main Authors: Anicca D. Harriot, Tessa Altair Morris, Camilo Vanegas, Jacob Kallenbach, Kaylie Pinto, Humberto C. Joca, Marie-Jo Moutin, Guoli Shi, Jeanine A. Ursitti, Anna Grosberg, Christopher W. Ward
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
dystrophy
skeletal muscle
myoarchitecture
microtubule array
detyrosination
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1209542/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1209542/full

Similar Items