Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers

Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers

Altered myofibrillar structure is a consequence of dystrophic pathology that impairs skeletal muscle contractile function and increases susceptibility to contraction injury. In murine Duchenne muscular dystrophy (mdx), myofibrillar alterations are abundant in advanced pathology (>4 months), a...

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Bibliographic Details
Main Authors:	Anicca D. Harriot, Tessa Altair Morris, Camilo Vanegas, Jacob Kallenbach, Kaylie Pinto, Humberto C. Joca, Marie-Jo Moutin, Guoli Shi, Jeanine A. Ursitti, Anna Grosberg, Christopher W. Ward
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	dystrophy skeletal muscle myoarchitecture microtubule array detyrosination
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1209542/full

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