Polymer-encased nanodiscs with improved buffer compatibility

Abstract Styrene-maleic acid copolymers allow for solubilization and reconstitution of membrane proteins into nanodiscs. These polymer-encased nanodiscs are promising platforms for studies of membrane proteins in a near-physiologic environment without the use of detergents. However, current styrene-...

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Bibliographic Details
Main Authors: Mariana C. Fiori, Yunjiang Jiang, Guillermo A. Altenberg, Hongjun Liang
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07110-1