HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection

HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection

The role of hypoxia inducible factors in infection and immune response is unclear. Here, the authors study their impact on the regulation of T cells responses during Mycobacteria tuberculosis infection using transcriptomics, flow cytometry and in vivo infection.

Bibliographic Details
Main Authors: Ruining Liu, Victoria Muliadi, Wenjun Mou, Hanxiong Li, Juan Yuan, Johan Holmberg, Benedict J. Chambers, Nadeem Ullah, Jakob Wurth, Mohammad Alzrigat, Susanne Schlisio, Berit Carow, Lars Gunnar Larsson, Martin E. Rottenberg
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32639-9

Internet

https://doi.org/10.1038/s41467-022-32639-9

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