Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis

Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis

Prevalence of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) higher in men than premenopausal women. Here the authors report that formyl peptide receptor 2 (FPR2) levels are regulated by estrogen, and that FPR2 contributes to NAFLD resistance in female mice.

Bibliographic Details
Main Authors: Chanbin Lee, Jieun Kim, Jinsol Han, Dayoung Oh, Minju Kim, Hayeong Jeong, Tae-Jin Kim, Sang-Woo Kim, Jeong Nam Kim, Young-Su Seo, Ayako Suzuki, Jae Ho Kim, Youngmi Jung
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28138-6

Internet

https://doi.org/10.1038/s41467-022-28138-6

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