Patient-Derived Cancer-Associated Fibroblasts Support the Colonization of Tumor Cells in Head and Neck Squamous Cell Carcinoma

Patient-Derived Cancer-Associated Fibroblasts Support the Colonization of Tumor Cells in Head and Neck Squamous Cell Carcinoma

<b>Background:</b> The crosstalk between cancer-associated fibroblasts (CAFs) and tumor cells promotes proliferation, tumor relapse, and the acquisition of a partial epithelial-to-mesenchymal (pEMT) phenotype in tumor cells. The aim of this study was to investigate the effects of patient...

Full description

Bibliographic Details
Main Authors: Julia Federspiel, Teresa Bernadette Steinbichler, Samuel Moritz Vorbach, Marie Theres Eling, Wegene Borena, Christof Seifarth, Benedikt Gabriel Hofauer, Jozsef Dudas
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
patient-derived cell culture
cancer-associated fibroblasts (CAFs)
head and neck squamous cell carcinoma (HNSCC)
irradiation
tumor cell relapse
Online Access:https://www.mdpi.com/2227-9059/13/2/358

Internet

https://www.mdpi.com/2227-9059/13/2/358

Similar Items