3D-Cultured Adipose-Derived Stem Cell Spheres Using Calcium-Alginate Scaffolds for Osteoarthritis Treatment in a Mono-Iodoacetate-Induced Rat Model

3D-Cultured Adipose-Derived Stem Cell Spheres Using Calcium-Alginate Scaffolds for Osteoarthritis Treatment in a Mono-Iodoacetate-Induced Rat Model

Osteoarthritis (OA) is a degenerative disease that causes pain, cartilage deformation, and joint inflammation. Mesenchymal stem cells (MSCs) are potential therapeutic agents for OA treatment. However, the 2D culture of MSCs could potentially affect their characteristics and functionality. In this st...

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Bibliographic Details
Main Authors: Yu-Ying Lin, Che-Yung Kuan, Chia-Tien Chang, Ming-Hsi Chuang, Wan-Sin Syu, Kai-Ling Zhang, Chia-Hsin Lee, Po-Cheng Lin, Guo-Chung Dong, Feng-Huei Lin
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
osteoarthritis
human adipose-derived stem cells
cell spheres
alginate
monosodium iodoacetate
Online Access:https://www.mdpi.com/1422-0067/24/8/7062

Internet

https://www.mdpi.com/1422-0067/24/8/7062

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