Improved multilineage human hematopoietic reconstitution and function in NSGS mice.

Improved multilineage human hematopoietic reconstitution and function in NSGS mice.

Genetic manipulation of NOD/SCID (NS) mice has yielded numerous sub-strains with specific traits useful for the study of human hematopoietic xenografts, each with unique characteristics. Here, we have compared the engraftment and output of umbilical cord blood (UCB) CD34+ cells in four immune-defici...

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Bibliographic Details
Main Authors: Mark Wunderlich, Fu-Sheng Chou, Christina Sexton, Pietro Presicce, Claire A Chougnet, Julio Aliberti, James C Mulloy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209034

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https://doi.org/10.1371/journal.pone.0209034

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