Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin.

Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin.

The influenza virus causes acute respiratory infections, leading to high morbidity and mortality in groups of patients at higher risk. Antiviral drugs represent the first line of defense against influenza, both for seasonal infections and pandemic outbreaks. Two main classes of drugs against influen...

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Bibliographic Details
Main Authors: Carolina Q Sacramento, Andressa Marttorelli, Natalia Fintelman-Rodrigues, Caroline S de Freitas, Gabrielle R de Melo, Marco E N Rocha, Carlos R Kaiser, Katia F Rodrigues, Gisela L da Costa, Cristiane M Alves, Osvaldo Santos-Filho, Jussara P Barbosa, Thiago Moreno L Souza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4603893?pdf=render

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http://europepmc.org/articles/PMC4603893?pdf=render

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