Molecular structure of an amyloid fibril formed by FUS low-complexity domain
Summary: FUS is a multifunctional nuclear protein which undergoes liquid–liquid phase separation in response to stress and DNA damage. Dysregulation of FUS dynamic phase separation leads to formation of pathological fibril closely associated with neurodegenerative diseases such as amyotrophic latera...
| Hoofdauteurs: | , , , , , , , , , |
|---|---|
| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Elsevier
2022-01-01
|
| Reeks: | iScience |
| Onderwerpen: | |
| Online toegang: | http://www.sciencedirect.com/science/article/pii/S2589004221016710 |