Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?

Cigarette smoking induces inflammatory responses in all smokers and is the major risk factor for lung disease such as chronic obstructive pulmonary disease (COPD). In this progressive disease, chronic inflammation in the lung contributes to lung tissue destruction leading to the formation of chemota...

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Bibliographic Details
Main Authors: Saskia A Overbeek, Saskia Braber, Pim J Koelink, Paul A J Henricks, Esmaeil Mortaz, Adele T LoTam Loi, Patricia L Jackson, Johan Garssen, Gerry T M Wagenaar, Wim Timens, Leo Koenderman, J Edwin Blalock, Aletta D Kraneveld, Gert Folkerts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561332?pdf=render