Theoretical activity prediction, structure-based design, molecular docking and pharmacokinetic studies of some maleimides against Leishmania donovani for the treatment of leishmaniasis

Abstract Background Leishmaniasis is a neglected tropical disease caused by a group of protozoan of the genus Leishmania and transmitted to humans majorly through the bite of the female sand fly. It is prevalent in the tropical regions of the world especially in Africa and estimated to affect a popu...

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Bibliographic Details
Main Authors: Fabian Audu Ugbe, Gideon Adamu Shallangwa, Adamu Uzairu, Ibrahim Abdulkadir
Format: Article
Language:English
Published: SpringerOpen 2022-04-01
Series:Bulletin of the National Research Centre
Subjects:
Online Access:https://doi.org/10.1186/s42269-022-00779-z