A systems genomics approach uncovers molecular associates of RSV severity.

Respiratory syncytial virus (RSV) infection results in millions of hospitalizations and thousands of deaths each year. Variations in the adaptive and innate immune response appear to be associated with RSV severity. To investigate the host response to RSV infection in infants, we performed a systems...

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Bibliographic Details
Main Authors: Matthew N McCall, Chin-Yi Chu, Lu Wang, Lauren Benoodt, Juilee Thakar, Anthony Corbett, Jeanne Holden-Wiltse, Christopher Slaunwhite, Alex Grier, Steven R Gill, Ann R Falsey, David J Topham, Mary T Caserta, Edward E Walsh, Xing Qiu, Thomas J Mariani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1009617&type=printable