Loss of TACC1 variant25 inducing cell proliferation and suppressing autophagy in head and neck squamous carcinoma
Abstract Transforming acidic coiled-coil containing protein1 (TACC1) is closely related to transcription, translation and centrosome dynamics. Dysregulation of TACC1 is associated with multiple malignancies. Alternative splicing (AS) of TACC1 produces multiple variants, which are of great significan...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-12-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00777-6 |