Loss of TACC1 variant25 inducing cell proliferation and suppressing autophagy in head and neck squamous carcinoma

Abstract Transforming acidic coiled-coil containing protein1 (TACC1) is closely related to transcription, translation and centrosome dynamics. Dysregulation of TACC1 is associated with multiple malignancies. Alternative splicing (AS) of TACC1 produces multiple variants, which are of great significan...

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Bibliographic Details
Main Authors: Pan Xu, Ran Zhao, Chen-Yang Zhang, Qian-Qian Zhang, Yong Wang, Jun Zhu, Wei-Wen Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2021-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00777-6