The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis

The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis

The differentiation of fibroblasts into pathological myofibroblasts during wound healing is characterized by increased cell surface expression of αv-integrins. Our previous studies found that the deubiquitinase (DUB) USP10 removes ubiquitin from αv-integrins, leading to cell surface integrin accumul...

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Bibliographic Details
Main Authors: Andrew T. Phillips, Edward F. Boumil, Arunkumar Venkatesan, Christine Tilstra-Smith, Nileyma Castro, Barry E. Knox, Jessica L. Henty-Ridilla, Audrey M. Bernstein
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:European Journal of Cell Biology
Subjects:
Myofibroblast
Integrin
Fibrosis
Scarring
Formin
Ubiquitin
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000626

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http://www.sciencedirect.com/science/article/pii/S0171933523000626

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