Gynecologic and breast cancers with hereditary cancer predisposition syndromes

Approximately 20–25% of ovarian cancers, 5–10% of uterine cancers, and 5–10% of breast cancers are attributable to inherited pathogenic genetic alterations. Identifying characteristic germline mutations is crucial for patient management, as appropriate surveillance and further surgical interventions...

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Bibliographic Details
Main Authors: Courtney F. Connelly, Sudarshana Roychoudhury, Yan Peng, Hua Guo, Roshni Rao
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Human Pathology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772736X24000367