Asparagine endopeptidase deficiency mitigates radiation-induced brain injury by suppressing microglia-mediated neuronal senescence

Asparagine endopeptidase deficiency mitigates radiation-induced brain injury by suppressing microglia-mediated neuronal senescence

Summary: Mounting evidence supports the role of neuroinflammation in radiation-induced brain injury (RIBI), a chronic disease characterized by delayed and progressive neurological impairment. Asparagine endopeptidase (AEP), also known as legumain (LGMN), participates in multiple malignancies and neu...

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Dades bibliogràfiques
Autors principals: Ouwen Qiu, Jianyi Zhao, Zhonggang Shi, Huan Li, Siyuan Wang, Keman Liao, Minchao Tang, Jieqiong Xie, Xi Huang, Wenrui Zhang, Li Zhou, Xi Yang, Zhiyi Zhou, Lei Xu, Renhua Huang, Yifeng Miao, Yongming Qiu, Yingying Lin
Format: Article
Idioma:English
Publicat: Elsevier 2024-05-01
Col·lecció:iScience
Matèries:
Molecular biology
Neuroscience
Immunology
Omics
Metabolomics
Transcriptomics
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2589004224009209

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224009209

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