Generation of Human iPSC–Derived Intestinal Epithelial Cell Monolayers by CDX2 TransductionSummary

Generation of Human iPSC–Derived Intestinal Epithelial Cell Monolayers by CDX2 TransductionSummary

Background & aims: To develop an effective and safe orally administered drug, it is important to predict its intestinal absorption rate, intestinal first-pass effect, and drug-drug interactions of orally administered drugs. However, there is no existing model to comprehensively predict the intes...

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Bibliographic Details
Main Authors: Kazuo Takayama, Ryosuke Negoro, Tomoki Yamashita, Kanae Kawai, Moe Ichikawa, Takanori Mori, Noriyuki Nakatsu, Kazuo Harada, Sumito Ito, Hiroshi Yamada, Yoshiyuki Yamaura, Kazumasa Hirata, Seiichi Ishida, Hiroyuki Mizuguchi
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300827

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http://www.sciencedirect.com/science/article/pii/S2352345X19300827

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