Editing out HIV: application of gene editing technology to achieve functional cure

Abstract Highly active antiretroviral therapy (HAART) successfully suppresses human immunodeficiency virus (HIV) replication and improves the quality of life of patients living with HIV. However, current HAART does not eradicate HIV infection because an HIV reservoir is established in latently infec...

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Bibliographic Details
Main Authors: Jingna Xun, Xinyu Zhang, Shuyan Guo, Hongzhou Lu, Jun Chen
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Retrovirology
Subjects:
Online Access:https://doi.org/10.1186/s12977-021-00581-1