Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

<p>Abstract</p> <p>Background</p> <p>Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmune encephalomyelitis (EAE...

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Bibliographic Details
Main Authors: Hohlfeld Reinhard, von Bubnoff Nikolas, Kümpfel Tania, Hapfelmeier Alexander, Hertzenberg Deetje, Schleich Eva, Lehmann-Horn Klaus, Berthele Achim, Hemmer Bernhard, Weber Martin S
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Journal of Neuroinflammation
Subjects:
multiple sclerosis
neuromyelitis optica
anti-CD20
B-cell regulation
monocytes
experimental autoimmune encephalomyelitis
Online Access:http://www.jneuroinflammation.com/content/8/1/146

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http://www.jneuroinflammation.com/content/8/1/146

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