Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia

Orphan Nuclear Receptor Family 4A (NR4A) Members NR4A2 and NR4A3 Selectively Modulate Elements of the Monocyte Response to Buffered Hypercapnia

Hypercapnia occurs when the partial pressure of carbon dioxide (CO<sub>2</sub>) in the blood exceeds 45 mmHg. Hypercapnia is associated with several lung pathologies and is transcriptionally linked to suppression of immune and inflammatory signalling through poorly understood mechanisms....

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Bibliographic Details
Main Authors: David E. Phelan, Ben Reddan, Masahiko Shigemura, Jacob I. Sznajder, Daniel Crean, Eoin P. Cummins
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
hypercapnia
carbon dioxide
CO<sub>2</sub>
orphan nuclear receptor family 4A
NR4A2
NR4A3
Online Access:https://www.mdpi.com/1422-0067/25/5/2852

Internet

https://www.mdpi.com/1422-0067/25/5/2852

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