The Pluripotency Factor Nanog Protects against Neuronal Amyloid β-Induced Toxicity and Oxidative Stress through Insulin Sensitivity Restoration

The Pluripotency Factor Nanog Protects against Neuronal Amyloid β-Induced Toxicity and Oxidative Stress through Insulin Sensitivity Restoration

Amyloid β (Aβ) is a peptide fragment of the amyloid precursor protein that triggers the progression of Alzheimer’s Disease (AD). It is believed that Aβ contributes to neurodegeneration in several ways, including mitochondria dysfunction, oxidative stress and brain insulin resistance. Therefore, prot...

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Bibliographic Details
Main Authors: Ching-Chi Chang, Hsin-Hua Li, Sing-Hua Tsou, Hui-Chih Hung, Guang-Yaw Liu, Tatiana A. Korolenko, Te-Jen Lai, Ying-Jui Ho, Chih-Li Lin
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
amyloid β
insulin signaling
oxidative stress
Nanog
senescence
Online Access:https://www.mdpi.com/2073-4409/9/6/1339

Internet

https://www.mdpi.com/2073-4409/9/6/1339

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