Development of an Integrated Continuous Manufacturing Process for the rVSV-Vectored SARS-CoV-2 Candidate Vaccine

Development of an Integrated Continuous Manufacturing Process for the rVSV-Vectored SARS-CoV-2 Candidate Vaccine

The administration of viral vectored vaccines remains one of the most effective ways to respond to the ongoing novel coronavirus disease 2019 (COVID-19) pandemic. However, pre-existing immunity to the viral vector hinders its potency, resulting in a limited choice of viral vectors. Moreover, the bas...

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Bibliographic Details
Main Authors: Zeyu Yang, Barbara Cristina Martins Fernandes Paes, Julia Puppin Chaves Fulber, Michelle Yen Tran, Omar Farnós, Amine A. Kamen
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Vaccines
Subjects:
COVID-19
SARS-CoV-2
viral vectored vaccine
recombinant vesicular stomatitis virus
perfusion
upstream process
Online Access:https://www.mdpi.com/2076-393X/11/4/841

Internet

https://www.mdpi.com/2076-393X/11/4/841

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