Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity

<p>Abstract</p> <p>Background</p> <p>The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorige...

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Bibliographic Details
Main Authors: Roh Meejeon, Kim Jongchan, Abdulkadir Sarki A
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/248