A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain

A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain

Abstract Glutamate receptors of the N-methyl-D-aspartate (NMDA) family are coincident detectors of pre- and postsynaptic activity, allowing Ca2+ influx into neurons. These properties are central to neurological disease mechanisms and are proposed to be the basis of associative learning and memory. I...

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Bibliographic Details
Main Authors: Hannah Warming, Chrysia-Maria Pegasiou, Aleksandra P. Pitera, Hanna Kariis, Steven D. Houghton, Ksenia Kurbatskaya, Aminul Ahmed, Paul Grundy, Girish Vajramani, Diederik Bulters, Xavier Altafaj, Katrin Deinhardt, Mariana Vargas-Caballero
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Molecular Brain
Subjects:
NMDA receptor
Synapses
Human
Primate
Resected
Neurosurgery
Online Access:http://link.springer.com/article/10.1186/s13041-019-0485-9

Internet

http://link.springer.com/article/10.1186/s13041-019-0485-9

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