Survival and Chemosensitivity in Advanced High Grade Serous Epithelial Ovarian Cancer Patients with and without a BRCA Germline Mutation: More Evidence for Shifting the Paradigm towards Complete Surgical Cytoreduction

Survival and Chemosensitivity in Advanced High Grade Serous Epithelial Ovarian Cancer Patients with and without a BRCA Germline Mutation: More Evidence for Shifting the Paradigm towards Complete Surgical Cytoreduction

<i>Background and Objectives</i>: Approximately 10–15% of high-grade serous ovarian cancer (HGSOC) cases are related to BRCA germline mutations. Better survival rates and increased chemosensitivity are reported in patients with a BRCA 1/2 germline mutation. However, the FIGO stage and hi...

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Bibliographic Details
Main Authors: Diederick De Jong, Mohamed Otify, Inga Chen, David Jackson, Kelum Jayasinghe, David Nugent, Amudha Thangavelu, Georgios Theophilou, Alexandros Laios
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medicina
Subjects:
BRCA status
complete cytoreduction
chemotherapy response score
epithelial ovarian cancer
CA125
Online Access:https://www.mdpi.com/1648-9144/58/11/1611

Internet

https://www.mdpi.com/1648-9144/58/11/1611

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