Transmucosal Solid Lipid Nanoparticles to Improve Genistein Absorption via Intestinal Lymphatic Transport

Transmucosal Solid Lipid Nanoparticles to Improve Genistein Absorption via Intestinal Lymphatic Transport

Genistein (GEN) is a soy-derived isoflavone that exhibits several biological effects, such as neuroprotective activity and the prevention of several types of cancer and cardiovascular disease. However, due to its poor water solubility and the extensive first-pass metabolism, the oral bioavailability...

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Bibliographic Details
Main Authors: Antonella Obinu, Giovanni Pietro Burrai, Roberta Cavalli, Grazia Galleri, Rossana Migheli, Elisabetta Antuofermo, Giovanna Rassu, Elisabetta Gavini, Paolo Giunchedi
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
solid lipid nanoparticles
genistein
oral bioavailability
intestinal lymphatic absorption
Online Access:https://www.mdpi.com/1999-4923/13/2/267

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https://www.mdpi.com/1999-4923/13/2/267

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