The roles of transmembrane domain helix-III during rhodopsin photoactivation.

Rhodopsin, the prototypic member of G protein-coupled receptors (GPCRs), undergoes isomerization of 11-cis-retinal to all-trans-retinal upon photoactivation. Although the basic mechanism by which rhodopsin is activated is well understood, the roles of whole transmembrane (TM) helix-III during rhodop...

Full description

Bibliographic Details
Main Authors: Wen-bin Ou, Tingfang Yi, Jong-Myoung Kim, H Gobind Khorana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3045455?pdf=render