Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak.
The heart develops from 2 sources of mesoderm progenitors, the first and second heart field (FHF and SHF). Using a single-cell transcriptomic assay combined with genetic lineage tracing and live imaging, we find the FHF and SHF are subdivided into distinct pools of progenitors in gastrulating mouse...
| Главные авторы: | , , , , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Public Library of Science (PLoS)
2021-05-01
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| Серии: | PLoS Biology |
| Online-ссылка: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001200&type=printable |