Dynamic actin/septin network in megakaryocytes coordinates proplatelet elaboration

Megakaryocytes (MK) undergo extensive cytoskeletal rearrangements as they give rise to platelets. While cortical microtubule sliding has been implicated in proplatelet formation, the role of the actin cytoskeleton in proplatelet elongation is less understood. It is assumed that actin filament reorg...

Full description

Bibliographic Details
Main Authors: Isabelle C. Becker, Adrian R. Wilkie, Bret A. Unger, Anthony R. Sciaudone, Farheen Fatima, I-Ting Tsai, Ke Xu, Kellie R. Machlus, Joseph E. Italiano
Format: Article
Language:English
Published: Ferrata Storti Foundation 2023-09-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11252