Genome-wide analysis of copy number variation identifies candidate gene loci associated with the progression of non-alcoholic fatty liver disease.

Between 10 and 25% of individuals with non-alcoholic fatty liver disease (NAFLD) develop hepatic fibrosis leading to cirrhosis and hepatocellular carcinoma (HCC). To investigate the molecular basis of disease progression, we performed a genome-wide analysis of copy number variation (CNV) in a total...

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Main Authors: Shamsul Mohd Zain, Rosmawati Mohamed, David N Cooper, Rozaimi Razali, Sanjay Rampal, Sanjiv Mahadeva, Wah-Kheong Chan, Arif Anwar, Nurul Shielawati Mohamed Rosli, Anis Shafina Mahfudz, Phaik-Leng Cheah, Roma Choudhury Basu, Zahurin Mohamed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24743702/pdf/?tool=EBI