Spatiotemporal dynamics of multi-vesicular release is determined by heterogeneity of release sites within central synapses

A synaptic active zone (AZ) can release multiple vesicles in response to an action potential. This multi-vesicular release (MVR) occurs at most synapses, but its spatiotemporal properties are unknown. Nanoscale-resolution detection of individual release events in hippocampal synapses revealed unprec...

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Bibliographic Details
Main Authors: Dario Maschi, Vitaly A Klyachko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/55210