Micro-Scale Distribution of CA4+ in Ex vivo Human Articular Cartilage Detected with Contrast-Enhanced Micro-Computed Tomography Imaging

Contrast-enhanced micro-computed tomography (CEμCT) with cationic and anionic contrast agents reveals glycosaminoglycan (GAG) content and distribution in articular cartilage (AC). The advantage of using cationic stains (e.g., CA4+) compared to anionic stains (e.g., Hexabrix®), is that it distributes...

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Bibliographic Details
Main Authors: Sakari S. Karhula, Mikko A. Finnilä, Jonathan D. Freedman, Sami Kauppinen, Maarit Valkealahti, Petri Lehenkari, Kenneth P. H. Pritzker, Heikki J. Nieminen, Brian D. Snyder, Mark W. Grinstaff, Simo Saarakkala
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Physics
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Online Access:http://journal.frontiersin.org/article/10.3389/fphy.2017.00038/full