Urolithin B: Two-way attack on IAPP proteotoxicity with implications for diabetes

Urolithin B: Two-way attack on IAPP proteotoxicity with implications for diabetes

IntroductionDiabetes is one of the major metabolic diseases worldwide. Despite being a complex systemic pathology, the aggregation and deposition of Islet Amyloid Polypeptide (IAPP), or amylin, is a recognized histopathological marker of the disease. Although IAPP proteotoxicity represents an import...

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Bibliographic Details
Main Authors: Ana F. Raimundo, Sofia Ferreira, Vânia Pobre, Mafalda Lopes-da-Silva, José A. Brito, Daniel J. V. A. dos Santos, Nuno Saraiva, Cláudia N. dos Santos, Regina Menezes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
amylin
diabetes
IAPP
small molecule
urolithin B
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1008418/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1008418/full

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