The Dynamics of Nucleotide Variants in the Progression from Low–Intermediate Myeloma Precursor Conditions to Multiple Myeloma: Studying Serial Samples with a Targeted Sequencing Approach

The Dynamics of Nucleotide Variants in the Progression from Low–Intermediate Myeloma Precursor Conditions to Multiple Myeloma: Studying Serial Samples with a Targeted Sequencing Approach

Multiple myeloma (MM), or Kahler’s disease, is an incurable plasma cell (PC) cancer in the bone marrow (BM). This malignancy is preceded by one or more asymptomatic precursor conditions, monoclonal gammopathy of undetermined significance (MGUS) and/or smoldering multiple myeloma (SMM). The molecular...

Full description

Bibliographic Details
Main Authors: Bénedith Oben, Charlotte Cosemans, Ellen Geerdens, Loes Linsen, Kimberly Vanhees, Brigitte Maes, Koen Theunissen, Bert Cruys, Marta Lionetti, Ingrid Arijs, Niccolò Bolli, Guy Froyen, Jean-Luc Rummens
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
multiple myeloma
monoclonal gammopathy of undetermined significance
smoldering multiple myeloma
progression
targeted sequencing
Online Access:https://www.mdpi.com/2072-6694/14/4/1035

Internet

https://www.mdpi.com/2072-6694/14/4/1035

Similar Items