KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation.

KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation.

Kaposi's sarcoma associated herpesvirus (KSHV) persists in a highly-ordered chromatin structure inside latently infected cells with the majority of the viral genome having repressive marks. However, upon reactivation the viral chromatin landscape changes into 'open' chromatin through...

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Bibliographic Details
Main Authors: Roxanne C Strahan, Maria McDowell-Sargent, Timsy Uppal, Pravinkumar Purushothaman, Subhash C Verma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5513536?pdf=render

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http://europepmc.org/articles/PMC5513536?pdf=render

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