Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer

The identification of cell types of origin for cancer has important implications for tumor stratification and personalized treatment. For prostate cancer, the cell of origin has been intensively studied, but it has remained unclear whether basal or luminal epithelial cells, or both, represent cells...

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Bibliographic Details
Main Authors: Zhu A. Wang, Roxanne Toivanen, Sarah K. Bergren, Pierre Chambon, Michael M. Shen
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714006615