The Interplay between Intracellular Iron Homeostasis and Neuroinflammation in Neurodegenerative Diseases

Iron is essential for life. Many enzymes require iron for appropriate function. However, dysregulation of intracellular iron homeostasis produces excessive reactive oxygen species (ROS) via the Fenton reaction and causes devastating effects on cells, leading to ferroptosis, an iron-dependent cell de...

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Bibliografiske detaljer
Main Authors: Jaewang Lee, Dong-Hoon Hyun
Format: Article
Sprog:English
Udgivet: MDPI AG 2023-04-01
Serier:Antioxidants
Fag:
Online adgang:https://www.mdpi.com/2076-3921/12/4/918