Effects of genetic variants in the TSPO gene on protein structure and stability.

Effects of genetic variants in the TSPO gene on protein structure and stability.

The 18 kDa translocator protein (TSPO) is an evolutionary conserved cholesterol binding protein localized in the outer mitochondrial membrane. Expression of TSPO is upregulated in activated microglia in various neuroinflammatory, neurodegenerative, and neoplastic disorders. Therefore, TSPO radioliga...

Full description

Bibliographic Details
Main Authors: Vladimir M Milenkovic, Stefanie Bader, Daniel Sudria-Lopez, Ramona Siebert, Caroline Brandl, Caroline Nothdurfter, Bernhard H F Weber, Rainer Rupprecht, Christian H Wetzel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5895031?pdf=render

Internet

http://europepmc.org/articles/PMC5895031?pdf=render

Similar Items