SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance

SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance

Object: The aims of the study were to explore the protective effects of S-propargyl-cysteine (SPRC) on periodontitis and to determine the underlying mechanisms.Methods: A rat periodontitis model was constructed by injecting LPS and SPRC (0, 25, and 50 mg/kg/d) was administered intraperitoneally. H2S...

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Bibliographic Details
Main Authors: Qian Peng, Bingkun Zhao, Jie Lin, Haixia Liu, Rong Zhou, Dongmei Lan, Chao Yao, Shaohua Cong, Shen Tao, Yizhun Zhu, Raorao Wang, Shengcai Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
S-propargyl-cysteine
periodontitis
Th17 cells
regulatory T cells
ERK/CREB signalling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.737334/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2021.737334/full

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